Gabapentin And CBD Oil For Dogs


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Your dog is in chronic pain and the vet just prescribed Gabapentin — now what? Find out the truth about this medication and if it's the right choice. CBD and Gabapentin For Dogs: Can Dogs Take CBD and Gabapentin? Cannanine™ Ultra-Premium Hemp Oil (250mg, 500mg, 1000mg) $69.99 – $129.99 $39.99 – $99.99 The most potent and cost effective Dogs receiving chemotherapy for cancer tend to have a lot of unwanted side effects. Many pet parents use CBD oil as a way to curb some of them and make their pet more comfortable. Recent research has shown that giving CBD oil to your pet in conjunction with radiation actually may make chemotherapy more effective.

Gabapentin For Dogs: What Are The Side Effects?

When your dog is in pain all you want to do is help them as fast as you can. Nerve pain and seizures in your best friend can break your heart when you don’t know what to do.

But you can ease the suffering if you know what your dog needs to stay happy and healthy. Vets have all sorts of solutions for different illnesses, and a common treatment for seizures and pain in dogs is Gabapentin.

When your vet prescribes Gabapentin, it can be overwhelming and confusing if they don’t have time to fully explain the drug. In this article, we will break down every question you could have, and explore whether the use of Gabapentin is the right choice for dogs’ experience with chronic pain.

What Is Gabapentin?

Gabapentin is a medication that is commonly used to treat seizures and chronic pain in dogs. It works by inhibiting the transmission of pain signals along the nerves. Gabapentin is also sometimes used to treat anxiety, although this is less common.

The exact mechanism of action is not fully understood, but it is believed to work by binding to a specific site on the nervous system and modulating the activity of GABA, an inhibitory neurotransmitter.

Gabapentin treatment typically begins with a low dose that is gradually increased over time as needed. Side effects are generally rare, but may include sedation, vomiting, and diarrhea.

Gabapentin is generally safe and effective for most dogs, but as with any medication, there is always the potential for side effects. If you are considering gabapentin treatment for your dog, be sure to speak with your veterinarian first to make sure it is the right option for your pet.

What Is Gabapentin Used For In Treating Dogs?

Gabapentin is a drug commonly prescribed in veterinary medicine used to treat seizures, chronic pain, and nerve pain. Often given to humans with these symptoms, vets have recently begun prescribing it for dogs in distress as well. Although, you should know that Gabapentin is not FDA approved in dogs and is given “off-label.”

Gabapentin is a medication that is commonly used to treat pain in humans. However, it can also be used to treat veterinary patients, particularly dogs. Gabapentin works by reducing the ability of neurons to perceive pain. This makes it an effective pain medication for both humans and dogs.

In addition, gabapentin can also be used to treat seizures in dogs. Seizures are caused by abnormal electrical activity in the brain, and they can be very dangerous. Gabapentin helps to prevent seizures by reducing the excitability of neurons. As a result, it is an important medication for both humans and dogs.

Veterinary medicine has come a long way in recent years, and there are now a number of effective treatments for conditions that were once considered incurable. One such condition is epilepsy, which affects both humans and animals.

While there is no cure for epilepsy, gabapentin can help to control and treat seizures and ease the symptoms of the condition. It is typically used as an adjunctive therapy, which means it is usually given in conjunction with other seizure medications. Gabapentin is also used in conjunction with other pain medications, as it is effective in treating neuropathic pain.

In addition, gabapentin can also be used to treat anxiety and depression, both of which are common side effects of epilepsy. As a result, gabapentin can be a valuable tool in the treatment of epilepsy in dogs.

Gabapentin does not just block the pain receptors in the brain but fully relaxes the whole nervous system to stimulate deeper healing. This can make Gabapentin for dogs is a good choice for pain management when you need long-term care.

Is Gabapentin Safe For Dogs?

Like most medications, the use of Gabapentin for dogs is safe when you are closely monitoring the dosage and strength as prescribed by your vet. In general, this drug is considered safe for dogs and a good way to treat serious issues.

It is important to treat the right conditions with the right medication. If your dog has been diagnosed with depression or insomnia, make sure your vet knows this, as Gabapentin could be too strong when combined with medications for these conditions. However, it is important to be aware of potential drug interactions before giving this medication to your dog.

Never give human-grade Gabapentin to a dog as it contains Xylitol, which is toxic to dogs. Even small amounts of Xylitol can be extremely harmful, possibly leading to death. If you run out of your vet-prescribed medicine early, do not supplement it with anything but what your vet has approved.

The bottom line is that you always need to consult your vet and place your dog on a plan that is tailored to their specific needs.

Is Prescribed Gabapentin Safe for Senior Dogs?

Gabapentin is a veterinary medicine that is commonly used to manage chronic pain in dogs. It is safe, effective, and has fewer side effects than many other pain medications for senior dogs.

Gabapentin works by inhibiting the release of neurotransmitters that lead to pain signals. This helps to reduce the perception of pain and can provide significant relief for dogs suffering from arthritis or other degenerative joint diseases.

Additionally, gabapentin can help to reduce inflammation and swelling associated with chronic pain conditions. It is important to talk to your veterinarian before starting any new medication, but gabapentin is generally considered safe for senior dogs. When used as directed, it can provide significant relief from chronic pain and help improve quality of life for your aging dog.

When Is Gabapentin Prescribed For Dogs?

Since Gabapentin can be used to treat so many conditions, from arthritis to seizures, there are many situations when it is appropriate.

When dogs are recovering from surgery this drug can ease the pain and speed the healing process. A relaxed animal is less likely to pull out stitches or cause secondary complications from surgery. Due to its calming effects, Gabapentin can even be given to a fearful pup before a trip to the vet.

Gabapentin is also a known way to ease the symptoms of refractory seizures (seizures which haven’t responded to other medications) and epilepsy. It may be prescribed on its own or alongside other antiepileptic drugs.

It is also used in the treatment of chronic pain in dogs, especially that deemed to be of neuropathic origin. It’s thought to be most effective when used in conjunction with other analgesic agents like nonsteroidal anti-inflammatory drugs (NSAIDs).

Gabapentin Dosage For Dogs

For whatever reason your dog needs Gabapentin, you must make sure you’re giving the proper amount. The condition your dog is experiencing will affect the dosage levels. For example, the amount needed to treat seizures should not be equated with nerve pain.

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You and your vet need to work together to understand what your buddy needs. Gabapentin for dogs generally comes in smaller 100mg and 300mg dosages — the exact dose will correspond to your pet’s build and illness. Larger breeds in general need larger doses than small pups. Height, weight, and breed all contribute to figuring out the proper dosage.

Once your dog starts taking Gabapentin, it gets to work fairly quickly. Within one hour you should begin to see results, e.g. they behave more like their normal selves when not in distress. If they are still exhibiting pain symptoms after an hour or two after the dose was taken, do not administer another dose of the medication without consulting your vet.

One downside of Gabapentin is that it typically wears off in about 24 hours, meaning it may need to be administered every day to maintain results.

The medication is administered in pill form and works the fastest on an empty stomach, but if your dog has a hard time swallowing pills, then they can be taken with food as well.

Generally, a vet will start with the smallest dosage and adjust until the drug is working properly. You and your vet will determine the maximum possible dosage to prevent overdose from this drug.

Possible Gabapentin Side Effects In Dogs

Every medicine is going to come with some side effects. Understand the side effects of this drug so you don’t mistake the signs with something else.

Ask your vet if your pet is at high risk for any of these possible negative reactions:

  • Lack of coordination
  • Vomiting
  • Diarrhea

While intense side effects are rare, at the first sign of these serious symptoms you should cease giving Gabapentin and call your vet. You may have to alter the dosage levels or even find another drug or pain management option.

Let your vet know any and all drug allergies your dog has as well as their full medical history. This is especially important if your dog has kidney disease or has had renal failure in the past. Discuss a full medical history as well, especially any kidney issues or past renal failure. The vet will also need to know any other medications or supplements your dog takes, as Gabapentin could complicate or interfere with other substances.

Keep your eyes out for the possibility of an overdose. While generally not too dangerous, here are the main symptoms to be on the lookout for:

  • Sedation
  • Sudden diarrhea
  • Oversleeping
  • Bulging eyes
  • Falling over

If your pup exhibits any side effects from taking this drug, weigh the effects of Gabapentin for dogs against the possible consequences. Only give your fluffy friend what you and their doctor think will make them feel better and happy, and drugs are not always the answer!

Most Common Side Effects of Gabapentin

When it comes to your furry friend, you only want what’s best for them. So when your vet prescribes the veterinary medicine Gabapentin, you want to make sure you know all there is to know about the medication.

Gabapentin is a very safe medication, so there are very few adverse side effects related to it. Most commonly seen is sedation and stumbling. Starting at a lower dose and then gradually increasing may help reduce this effect.

Is it Safe to Stop Gabapentin Suddenly?

If you’re thinking about stopping Gabapentin for your dog, it’s important to be aware of the potential risks involved. Abruptly stopping the medication could make your dog’s symptoms worse, and in some cases, it could even be dangerous.

Withdrawal seizures are a possibility if you quit suddenly, so it’s important to speak to your veterinarian first. A missed dose here and there is not usually a problem, but if you miss a scheduled dose it’s important to give the next one as soon as possible.

And finally, be sure to follow the dosage instructions carefully – giving your dog too much or too little of the medication can have serious consequences. With all that being said, Gabapentin is generally a safe and effective medication for dogs, so don’t be afraid to ask your vet about it if you think it could help your furry friend.

Alternatives To Gabapentin For Dogs

If you are uncomfortable giving your dog medicine that is not FDA approved, there are safe, natural alternatives out there. If you’re interested in exploring herbal therapies for your dog, talk to your veterinarian about which treatments might be right for your pet.

In the past few years, CBD, or cannabidiol, has become a very popular option among pet owners to treat discomfort in pets. CBD activates serotonin receptors and helps your pooch relax, and has anti-inflammatory properties to help ease joint and nerve pain. CBD can be a great option to treat mild issues without the need for pharmaceuticals.

The anti-anxiety properties in CBD are a great way to calm your best friend on a trip to the vet without any side effects at the correct dosage. If medication doesn’t seem like the right choice for your pet at this point, explore some natural options.

Innovet Pet has all the CBD options you could want. From 100% Full Spectrum Golden CBD Oil to soothing CBD infused balms. Check out our CBD pet range today to find out what’s best for your canine companion.

Do The Best For Your Pet

Innovet Pet was founded by dog lovers, and we know just how hard it is to see your dog suffering. That’s why we guarantee our products will help ease discomfort.

We work with vets to make sure all our products are 100% pet-safe. So, if you’re unsure that prescribed medication is right for your dog, try our natural CBD solutions.


Dr. Ivana Vukasinovic

Doctor of Veterinary Medicine, University of Belgrade

Ivana Vukasinovic grew up in Serbia and attended the University of Belgrade where she received a degree in Veterinary medicine in 2012 and later completed surgical residency working mostly with livestock. Her first year of practice was split between busy small animal practice and emergency clinic, and after two more years of treating many different species of animals, she opened her own veterinary pharmacy where an interest in canine and feline nutrition emerged with an accent on fighting animal obesity. In her free time, she acts as a foster parent for stray animals before their adoption, likes to read SF books and making salted caramel cookies.

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The Innovet Team

Please do not ask for emergency or specific medical questions about your pets in the comments . Innovet Pet Products is unable to provide you with specific medical advice or counseling. A detailed physical exam, patient history, and an established veterinarian are required to provide specific medical advice. If you are worried that your pet requires emergency attention or if you have specific medical questions related to your pet’s current or chronic health conditions, please contact or visit your local/preferred veterinarian, an animal-specific poison control hotline, or your local emergency veterinary care center.

Please share your experiences and stories, your opinions and feedback about this blog, or what you’ve learned that you’d like to share with others.

CBD and Gabapentin For Dogs: Can Dogs Take CBD and Gabapentin?

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Gabapentin vs CBD Oil for Dogs

In the last 2 years, the popularity of cannabidiol (CBD) has exploded in popularity for dog owners seeking to manage pain & anxiety. CBD is often touted by some as a miracle drug, capable of curing nearly any ailment. The truth, however, is much more nuanced and while the industry is plagued by unrealistic promises for using CBD, actual research backed science is emerging that shows great promise for this hemp based compound.

In this beginner’s guide, we’ll introduce you to canine pain management using CBD. We’ll cover topics on the safety and legality of CBD, what scientific studies have shown, the success rates of using CBD on dogs, and choosing a quality product. We’ll conclude with a list of resources where you can learn more about CBD.

How CBD Works In Your Dog’s Body to Modulate Pain

The endocannabinoid system (ECS) is an interconnected chain of receptors found in your dog’s brain, their nervous system, glands, and organs. Scientists don’t fully understand the ECS yet (it was only first discovered in 1992) but its believed to help maintain balance within the body.

All mammals—humans, dogs, and cats included—rely the ECS system to regulate immune response. CBD oil interacts with the CB1 and CB2 receptors in your dog’s body and acts as a natural neuroprotective agent with multiple health benefits. The cannabinoids in the oil open up two-way communication between endocannabinoid receptors to allow the body to either increase or decrease the immune response as needed. CBD oil is the natural way of regulating the system to maintain the perfect balance.

The reason CBD seems to help modulate pain is that many dog’s bodies are deficient in cannabinoids. Supplementing with CBD increasing cannabinoids in the body and restores balance to the ECS system.

RELATED: 10 Myths Regarding CBD Oil and Dogs

Is It Safe To Use CBD and Gabapentin to Manage Pain for Dogs?

In 2016, Colorado State University completed a pharmacokinetic and safety study of CBD on healthy dogs. This was the first clinical trial to demonstrate that the cannabidiol compound was absorbed by the dogs and measurable in the blood. The study suggests that CBD usage in dogs is safe enough to warrant more studies. Source

For the study, 30 healthy dogs were given 2 different dosages CBD in 3 different methods of delivery: capsules, an oil tincture, and a cream applied on the skin. The results showed that CBD given orally as a tincture was best absorbed and bioavailable to the body. (This is why we recommend buying CBD in a tincture as your first choice).

What Scientific Studies or Clinical Trials Have Been Done on CBD for Pain Management for Dogs?

In addition to the safety and absorption study mentioned above, 3 clinical trials have recently concluded with promising results. It’s important to note that the we’re still in the early stages of understanding how CBD interacts with the body, and much more research needs to be done:

1. Cornell University: Osteoarthritis Pain Reduction in Dogs: Cornell University researchers found that CBD supplied by ElleVet Sciences increased comfort and the activity of dogs suffering from arthritis, according to a study published in July of 2018. This clinical study suggests that 2 mg/kg of CBD given twice daily can help increase comfort and activity in dogs with osteoarthritis. Source

2. Liberty Leaf: CBD Research Study on Canine Pain Management: In August of 2018, results from a randomized, placebo-controlled clinical trial demonstrated that dogs with diagnosed osteoarthritis receiving a daily dose of only 0.3 mg per kg of a CBD-infused oil formulation for 4 weeks showed reduced pain and improved functional performance.

3. Colorado State University: Reduction in Seizures for Dogs with Epilepsy: For 24 weeks, dogs that experience at least two seizures a month received either CBD oil treatment or a placebo. Preliminary results released in July of 2018 showed that a 89% of the dogs studied showed a drop in regular seizures.

How Successful is CBD At Managing Canine Pain?

iHeartDogs commissioned a survey that was completed by 455 people who gave CBD to to their dogs. The following data represents the responses of dog owners who gave CBD for pain management:

Survey Question: How effective do you feel the product was for your dog’s condition?

You can view the full survey results here.

How to Choose a Quality CBD from Hemp Product for Your Dog

Choosing a high quality CBD product can be confusing since the market is currently exploding and your options appear endless. Unfortunately, many brands do not perform 3rd party batch testing on their products to ensure the efficacy and purity.

We’ve put together a buying guide for CBD, containing 8 things to watch out for before making a purchase. You can receive the CBD Oil Buying Guide by by requesting it below:

What Real Dog Owners Say After Using CBD for Their Dog’s Pain

We asked members the iHeartSeniorDogs Facebook community for their experience with using CBD to alleviate their dog’s pain:

Cannanine CBD is currently the only CBD oil approved and recommended by

CBD has done wonders for our 11 year old Roti. You have to be very careful not to give them too much THC so choose your CBD carefully – Ken Tress

A lifesaver! I truly believe I would’ve already had to put her to sleep if not for it. – Suzanne Stanfield

The best thing I have ever done for my 200 pound Old English Mastiff was CBD oil she is 7 and we rescued her at 3 yrs old she was kept in a crate for 22 hours a day so she has terrible arthritis… so I medicate her 2 times a week and she runs and plays with my 2 puppers!! – Janell Michelle Cody

It’s been two weeks for our 13 year old pug and his hips are shot. His energy is back now, not jumping from pain when I pet him and is happy again. If I hadn’t tried this CBD oil I wouldn’t have believed it. Been a God send for my ole guy. I highly recommend it. Beats giving him pain meds which takes his spirit away. – Susan Johnson-Smith

I purchased Cannanine CBD oil for my two Bull Terriers for two different reasons. One is 8.5 yrs old and has arthritis. After a couple doses 1 per day there was an amazing improvement. She is up and playing and running around with my 2.5 yr. old. My 2.5 yr old is very excitable and we bring them both to our Sean soak campground. I tried it on her for calming effects. It seems to hit her the next day. Still experimenting with this. But for my 8.5 yr old it has brought back her quality of life. – Ann Fyfe

Some dog owners use CBD, but in addition to other supplements or prescription medications:

CBD and Gabapentin For Dogs

My dog is on Gabapentin along with CBD. No problems. – Mary Mueller

My dog is on Gabapentin and uses a 300mg cbd. It’s Really made a difference. He is 11. – Gene Sorensen

Good option but definitely not 1st line. Glucosamine Chondroitin MSM combo with Turmeric is a better 1st line options. Add CBD if this combo is not fully working by itself. –

My dog was on carprofen (generic rimadyl) and gabapentin for his arthritis pain. When I started him on cbd oil, I started with a much lower dose than what was recommended. Too much cbd too fast may cause issues like drowsiness or loose stool. While the cbd oil gradually increased, the other meds gradually decreased. As someone mentioned, it’s best to wean your dog off gabapentin slowly, don’t stop abruptly. My boy is only taking the cbd oil now and he is doing quite well. He even runs a little and he hasn’t run in years! Good luck with your pup! – Barbara Kalman LaVista

I am using Cannanine cbd oil along with turmeric paste. I couldn’t be happier with the results. – Pam Smith

Other dog owners saw results, but also had a few mild side-effects:

Fang (our 120lb..13 year old lab): has been on CBD oil for about 5- 6 weeks now and we’ve seen a noticeable improvement in his joint pain and overall movements. He’s able to walk up our 5 stairs with NO help and at times even takes off rather briskly up them. As of today, I would highly recommend CBD oil for older dog joint pain. We have noticed an increased appetite which has been a bit of a problem since he’s always had a rather enormous Lab appetite. We just focus on keeping his food intake the same to avoid weight gain…he can be a tiny bit hungry to be pain free. – Sinéad Daly Heath

One User’s Story: CBD for a 12 Year Old Immobile Dog

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We worked hard to create the Cannanine brand of CBD Oil. In addition to containing nano-sized emulsion (best for absorption) the formula is 100% THC free, which is relatively rare but very important for animal use.

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What Drugs Will Interact with My Pet’s CBD?

While we still do not even know the extent that people’s medications will interact with CBD, even less is known about pet CBD medication interactions. That is simply because the research is lacking for both, especially in the pet field.

My veterinarian will not talk to me about CBD, but I would still like to make an educated decision on whether or not giving them CBD would be for the best.

We understand that this can be a very frustrating issue for a lot of pet parents. While CBD can cause some pet medications to be more or even less effective if consumed with CBD, there are similar precautions that have to be taken when giving your pet herbal supplements or even vitamins. There is always going to be a chance of interactions. The extent of them depends on body chemistry and prescription dose. What will affect one pet, may not affect another.

When CBD is ingested orally at large doses a group of liver enzymes in your pet may be temporarily altered. One of the most common interactions that relate to this is grapefruit for humans. CBD is also metabolized by cytochrome P450 enzymes preventing it from metabolizing other compounds.

“The extent to which cannabidiol behaves as a competitive inhibitor of cytochrome P450 depends on how tightly CBD binds to the active site of the metabolic enzyme before and after oxidation. This can change greatly, depending on how – and how much – CBD is administered, the unique attributes of the individual taking this medication, and whether isolated CBD or a whole-plant remedy is used.” – Adrain Devitt-Lee, a researcher at Project CBD.

60% of all medications are metabolized in the liver via specific enzymes produced in it. CBD, like grapefruit, temporarily uses up the enzymes and/or inhibiting the action of others.

Drugs that may be used for pain relief in your pet such as NSAIDs (anti-inflammatory drugs), Tramadol, Gabapentin or anxiety relief such as Prozac all rely on the P450 enzymes. This does not mean your pet can’t take CBD, it just means you might want to be a little more careful when dosing it at first. And CBD can be a wonderful way to hopefully have your pet use less of the above medications.

NSAIDs can wreak havoc on the stomach and liver over long term use.

Tramadol and Gabapentin usually require an increased dose over time because the body gets used to it.

Prozac and any other anti-anxiety will have withdrawal symptoms if given over a period of time. Please do not ever take your pet off of these medications cold-turkey. It is very very important your pet is titrated down slowly off of them.

Here is how one of our clients uses CBD and Prozac together-

“I give my dog Blooming Culture pet CBD oil on a daily basis to help with her generalized anxiety. When we travel or fly I up her dose of CBD that day and add in her veterinarian prescribed Prozac. I have found in conjunction they work really well together for extreme circumstances.”

One of the biggest known and visible side-effects of dosing your pet CBD with any of these medications is tiredness, which can be easily remedied by adjusting their dose.

If you are thinking about switching your pet off their prescription medication or trying to lower their dose, do it slowly. You can first start with a low dose of CBD and talking to your veterinarian on the best way to ween off the particular medication.

All Drug Interactions are Not Negative

Since CBD can also enhance the effects of certain medications, this means that a lower dose of that medication or therapy can sometimes be used, which is a positive.

Drugs used for dog seizures is one. Since CBD also has its own anti-seizure properties, it has proven to work well in human clinical trials together with anti-seizure medications. The AKC Health Foundation recently announced that it will begin a major clinical trial to study the potential for pet CBD oil for use in drug-resistant epileptic dogs.

The second is chemotherapy. Dogs receiving chemotherapy for cancer tend to have a lot of unwanted side effects. Many pet parents use CBD oil as a way to curb some of them and make their pet more comfortable. The same way people going through radiation may use CBD or cannabis. But recent research has shown that giving CBD oil to your pet in conjunction with radiation actually may make chemotherapy more effective.

Some research states that CBD triggers TRPV2 channels, making the cancer cells more sensitive to chemotherapy.

A different study showed that rats with pancreatic cancer had 3X the survival rate when given CBD in conjunction with chemotherapy instead of only chemotherapy.

Again, please work with your veterinarian as much as possible to make sure every medication, natural or not is working together safely on your pet.

*This article is for informational purposes only. If you have pet medication interaction concerns, please always consult with your veterinarian first.

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